Photovoltaic retinal prosthesis

Photovoltaic retinal prosthesis ni tekinoroji yo kugarura amaso kubarwayi bahumwe nindwara zifata imyanya y'ijisho, nka retinitis pigmentosa hamwe na macula degeneration (AMD), mugihe abarwayi babuze 'ishusho ifata' fotorepteptors, ariko neuron muburyo bwo gutunganya amashusho. 'Imbere ya retina ibice byabitswe neza. Iyi prothèse subretinal yashizweho kugirango igarure amaso ikoresheje amashanyarazi itera imbere ya neurone y'imbere ikiriho, cyane cyane selile bipolar. Photovoltaic retinal yatewe ntago ari simusiga rwose kandi ikoreshwa na hafi-ya-infragre (880)nm) iteganijwe kuva mubirahuri byongerewe-ukuri. Kubura insinga ya trans-scleral byoroshya cyane uburyo bwo guterwa ugereranije nibindi byatewe. Gukoresha optique ya pigiseli ya Photovoltaque ituma gupima ibimera bigera ku bihumbi bya electrode kandi bikagumana guhuza bisanzwe kwimikorere yijisho kumyumvire. Ubushakashatsi bwakorewe ku mbeba hamwe no kwangirika kwa retine bwerekanye ko iyerekwa rya prostate hamwe nimbuto ziterwa na subretinal zirinda ibintu byinshi byerekezo karemano, harimo no guhuza flicker kuri radiyo nyinshi (> 20Hz), guhuza n'amashusho ahamye, antagonistic centre-ikikije organisation hamwe nincamake yumurongo wa subunits mumirima yakira, itanga imiterere ihanitse.

Amashusho yafashwe na kamera aratunganywa kandi akerekanwa kuri subretinal Photovoltaic yatewe mumirahuri yongerewe-ukuri ukoresheje urumuri rwa IR (880nm)

Photovoltaic array implanted under the degenerate retina converts NIR light into electric current flowing through the tissue and stimulating the inner retinal neurons.

Igeragezwa rya Clinical hamwe nigisekuru cya mbere cyatewe ( PRIMA, Pixium Vision) gifite pigiseli 100μm yerekanaga ko abarwayi ba AMD babona inyuguti nubundi buryo bufite imiterere ijyanye nubunini bwa pigiseli. Byongeye kandi, iyerekwa rya prothèque rwagati rifatwa icyarimwe hamwe nicyerekezo gisigaye cya periferique.

Photovoltaic array with 40μm pixels imaged on top of the retinal pigment epithelium.

Ibisekuru bizakurikiraho hamwe na pigiseli 20μm byatanze uburyo bwo gusya bujyanye nimiterere karemano yimbeba (28μm). Kugeza ubu, bene ibyo bisubizo bihanitse birimo gutezimbere retina yabantu nitsinda rya Palanker muri kaminuza ya Stanford .